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A 66-year-old woman had several episodes of aseptic meningitis associated with exposure to cephalexin,cefazolin,and ceftazidime.The cerebrospinal fluid IgG index was elevated,specific IgG-ceftazidime binding was shown, and skin allergy testing with cefazolin provoked a recurrence of meningitis.We postulate an acute hypersensitivity reaction involving an antigen-specific humoral immune response. |
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